Research at the Bischoff group at the University of Groningen (RUG) aims at the discovery and validation of disease-relevant biomarkers, the quantification of proteins (e.g. biopharmaceuticals) in complex biological matrices and the development of novel analytical techniques. The group collaborates closely with the GRIAC research institute (see below) in the area of respiratory disease. Among his other activities, Dr. Bischoff is the Dutch representative in the world-wide Human Proteome Project and has recently initiated a Respiratory Disease working group as part of HPP.
Dr. ten Hacken is a pulmonary physician at the University Medical Center Groningen (UMCG) and a member of the Groningen Research Institute on Asthma and COPD (GRIAC). The mission of the GRIAC is the multidisciplinary study of all aspects of obstructive airway and pulmonary diseases through interaction between clinicians and fundamental researchers. The main theme is unravelling the underlying mechanisms of the development and progression of airway obstruction, allergy, and airway hyper-responsiveness, and their mutual interactions. Chronic Obstructive Pulmonary Disease (COPD) is one the themes and the pulmonary department of the UMCG has a long record of studies on many aspects of this disabling disease.
Research at the Luider group at the Erasmus Medical Center (EMC)
focuses on the discovery and validation of biomarkers for brain tumors (e.g. glioblastoma), auto-immune disease and Alzheimer's Disease.
Dr. Luider collaborates closely with the
Research at the van Gool and Wevers research groups at the Radboud University Medical Center (RUMC) focuses on proteomics and metabolomics in relation to clinical chemistry challenges. Dr. van Gool heads the Radboud Centre for Proteomics, Glycomics and Metabolomics as well as the Radboudumc Technology Centers, which are high performance technological infrastructures supporting translation of biomedical research into applications in personalized healthcare. Dr. Wevers is head of a mixed-function laboratory with patient care and translational research, member of the Dutch Health Council and of its directory committee. The groups collaborate closely with the clinical research group of Dr. Tack on biomarkers for Diabetes Type II.
The Netherlands Organisation for Applied Scientific Research (TNO) works on development of innovative methods to improve disease prediction and to provide optimal medical treatment for each individual. Research focuses on the mechanistic cause as a fundament of disease development, with the aim to predict why a person develops the disease. Disease specific biomarkers, which are molecules that are present in blood or urine, enable us to reach this goal.